|Application ||WB, IHC-P, FC, E|
|Other Accession||P49401, P47836, NP_000999.1|
|Calculated MW||29456 Da|
|Antigen Region||76-105 aa|
|Other Names||40S ribosomal protein S4, Y isoform 1, RPS4Y1, RPS4Y|
|Target/Specificity||This RPS4Y1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human RPS4Y1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RPS4Y1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Agate, R.J., et al. Mol. Biol. Evol. 21(2):384-396(2004)
Vawter, M.P., et al. Neuropsychopharmacology 29(2):373-384(2004)
Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :
Skaletsky, H., et al. Nature 423(6942):825-837(2003)
Sampath, P., et al. Mol. Cell. Biol. 23(5):1509-1519(2003)
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