|Application ||WB, E|
|Calculated MW||20682 Da|
|Antigen Region||17-45 aa|
|Other Names||GTPase RhebL1, Ras homolog enriched in brain like-1 c, RhebL1c, Ras homolog enriched in brain-like protein 1, Rheb-like protein 1, Rheb2, RHEBL1|
|Target/Specificity||This RHEBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human RHEBL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RHEBL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.|
|Cellular Location||Endomembrane system; Lipid-anchor; Cytoplasmic side Cytoplasm|
|Tissue Location||Ubiquitously expressed. Expression increased at least 2-fold in several tumor cell lines|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
RHEBL1 binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Yuan, J., et al. Mol. Biol. Rep. 32(4):205-214(2005)
Tee, A.R., et al. FEBS Lett. 579(21):4763-4768(2005)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Tabancay, A.P. Jr., et al. J. Biol. Chem. 278(41):39921-39930(2003)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.