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RHEBL1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RHEBL1 Antibody (N-term) AP12804a
    RHEBL1 Antibody (N-term) (Cat. #AP12804a) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the RHEBL1 antibody detected the RHEBL1 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8TAI7
Other Accession NP_653194.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20682 Da
Antigen Region 17-45 aa
Additional Information
Gene ID 121268
Other Names GTPase RhebL1, Ras homolog enriched in brain like-1 c, RhebL1c, Ras homolog enriched in brain-like protein 1, Rheb-like protein 1, Rheb2, RHEBL1
Target/Specificity This RHEBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human RHEBL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRHEBL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RHEBL1
Function Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Cellular Location Endomembrane system; Lipid-anchor; Cytoplasmic side Cytoplasm
Tissue Location Ubiquitously expressed. Expression increased at least 2-fold in several tumor cell lines
Research Areas
Citations (0)

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Background

RHEBL1 binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.

References

Yuan, J., et al. Mol. Biol. Rep. 32(4):205-214(2005)
Tee, A.R., et al. FEBS Lett. 579(21):4763-4768(2005)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Tabancay, A.P. Jr., et al. J. Biol. Chem. 278(41):39921-39930(2003)

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$ 295.00
$ 99.00
Cat# AP12804a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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