|Application ||WB, E|
|Calculated MW||15641 Da|
|Antigen Region||88-116 aa|
|Other Names||Nuclear transition protein 2, TP-2, TP2, TNP2|
|Target/Specificity||This TNP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the C-terminal region of human TNP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TNP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.|
|Cellular Location||Nucleus. Chromosome.|
|Tissue Location||Expressed by spermatids (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)
Khattri, A., et al. Int. J. Androl. (2010) In press :
Pradeepa, M.M., et al. J. Biol. Chem. 284(43):29956-29967(2009)
Cooper, J.D., et al. Nat. Genet. 40(12):1399-1401(2008)
Becker, S., et al. Andrologia 40(4):203-208(2008)
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