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TNP2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TNP2 Antibody (C-term) AP12809b
    TNP2 Antibody (C-term) (Cat. #AP12809b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TNP2 antibody detected the TNP2 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q05952
Other Accession NP_005416.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 15641 Da
Antigen Region 88-116 aa
Additional Information
Gene ID 7142
Other Names Nuclear transition protein 2, TP-2, TP2, TNP2
Target/Specificity This TNP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the C-terminal region of human TNP2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTNP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNP2
Function In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.
Cellular Location Nucleus, nucleolus {ECO:0000250|UniProtKB:P11101}. Chromosome {ECO:0000250|UniProtKB:P11101}. Note=Nuclear import is ATP- dependent and nucleolar localization requires the protein to be phosphorylated. {ECO:0000250|UniProtKB:P11101}
Tissue Location Expressed by spermatids (at protein level).
Citations (0)

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Background

In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.

References

Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)
Khattri, A., et al. Int. J. Androl. (2010) In press :
Pradeepa, M.M., et al. J. Biol. Chem. 284(43):29956-29967(2009)
Cooper, J.D., et al. Nat. Genet. 40(12):1399-1401(2008)
Becker, S., et al. Andrologia 40(4):203-208(2008)

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Cat# AP12809b
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(40 western blots)
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