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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SYTL1 Antibody (Center)   

SYTL1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SYTL1 Antibody (Center) AP12814C
    SYTL1 Antibody (Center) (Cat. #AP12814c) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the SYTL1 antibody detected the SYTL1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IYJ3
Other Accession NP_001180237.1, NP_116261.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 61857 Da
Antigen Region 296-325 aa
Additional Information
Gene ID 84958
Other Names Synaptotagmin-like protein 1, Exophilin-7, Protein JFC1, SYTL1, SLP1
Target/Specificity This SYTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human SYTL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSYTL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYTL1
Synonyms SLP1
Function May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes
Tissue Location Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).
Research Areas
Citations (0)

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SYTL1 may play a role in vesicle trafficking (By similarity). It binds phosphatidylinositol 3,4,5-triphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity).


Neumuller, O., et al. Blood 114(7):1396-1404(2009)
Holt, O., et al. Traffic 9(4):446-457(2008)
Schmid, M., et al. J. Leukoc. Biol. 81(4):907-915(2007)
Johnson, J.L., et al. Biochem. J. 391 (PT 3), 699-710 (2005) :
Catz, S.D., et al. Biochem. J. 367 (PT 3), 791-799 (2002) :

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Cat# AP12814C
(40 western blots)
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