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BHMT2 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP12821c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12821c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
BHMT2 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q9H2M3 |
| Other Accession | NP_001171476.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 40354 Da |
BHMT2 Antibody (Center) - Additional info | |
| Gene ID 23743 | |
| Other Names BHMT2; S-methylmethionine--homocysteine S-methyltransferase BHMT2; Betaine--homocysteine S-methyltransferase 2 | |
| Target/Specificity This BHMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-142 amino acids from the Central region of human BHMT2. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions BHMT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
BHMT2 Antibody (Center) - Protein Information | |
| Name BHMT2 | |
| Function Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor | |
| Tissue Location Expressed in liver and kidney and at reduced levels in the brain, heart, and skeletal muscle | |
BHMT2 Antibody (Center) - Related products
AP12821c: BHMT2 Antibody (Center)
AP8762a: BHMT2 Antibody (N-term)
RI10590: BHMT2 predesign siRNA
DC04943: Human BHMT2 cDNA Clone
BHMT2 Antibody (Center) - Application data
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Western blot analysis of BHMT2 (arrow) using rabbit polyclonal BHMT2 Antibody (Center) (Cat. #AP12821c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the BHMT2 gene.
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BHMT2 Antibody (Center) (Cat. #AP12821c) western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the BHMT2 antibody detected the BHMT2 protein (arrow).
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BHMT2 Antibody (Center) (Cat. #AP12821c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BHMT2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
BHMT2 Antibody (Center) - Research Areas
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BACKGROUND
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
REFERENCES
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Giusti, B., et al. Thromb. Haemost. 104(2):231-242(2010) Mostowska, A., et al. Eur. J. Oral Sci. 118(4):325-332(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
