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GPM6A Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GPM6A Antibody (C-term) AP12829B
    GPM6A Antibody (C-term) (Cat. #AP12829b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GPM6A antibody detected the GPM6A protein (arrow).
  • IHC-P - GPM6A Antibody (C-term) AP12829B
    GPM6A Antibody (C-term) (Cat. #AP12829b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GPM6A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51674
Other Accession Q812E9, P35802, Q0VD07, NP_005268.1, NP_963886.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 31210 Da
Antigen Region 246-275 aa
Additional Information
Gene ID 2823
Other Names Neuronal membrane glycoprotein M6-a, M6a, GPM6A, M6A
Target/Specificity This GPM6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-275 amino acids from the C-terminal region of human GPM6A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGPM6A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPM6A
Synonyms M6A
Function Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons (By similarity).
Research Areas
Citations (0)

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Morrison, A.C., et al. Circ Cardiovasc Genet 3(3):248-255(2010)
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Michibata, H., et al. Stem Cells Dev. 18(4):629-639(2009)
Boks, M.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (6), 707-711 (2008) :
Liang, Y.J., et al. Cell Res. 18(7):768-779(2008)

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$ 295.00
$ 99.00
Cat# AP12829B
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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