GGT2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | P36268 |
Other Accession | A6NGU5, P19440 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 61771 Da |
Antigen Region | 12-40 aa |
Other Names | Inactive gamma-glutamyltranspeptidase 2, GGT 2, Gamma-glutamyltransferase 2, Glutathione hydrolase 2, GGT2 |
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Target/Specificity | This GGT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human GGT2. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GGT2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GGT2P (HGNC:4251) |
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Synonyms | GGT2 |
Function | [Isoform 1]: Lacks catalytic activity due to its inability to undergo the autocatalytic cleavage needed to produce a mature, enzymatically active heterodimer. |
Cellular Location | Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Co-localizes with calnexin in the endoplasmic reticulum |
Tissue Location | Highly expressed in fetal and adult kidney and liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
GGT2 initiates extracellular glutathione (GSH) breakdown; catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors (By similarity).
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