|Application ||WB, IHC-P, E|
|Other Accession||A6NGU5, P19440|
|Calculated MW||61771 Da|
|Antigen Region||12-40 aa|
|Other Names||Inactive gamma-glutamyltranspeptidase 2, GGT 2, Gamma-glutamyltransferase 2, Glutathione hydrolase 2, GGT2|
|Target/Specificity||This GGT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human GGT2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GGT2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1, isoform 2 and isoform 3 lack catalytic activity due to its inability to undergo the autocatalytic cleavage needed to produce a mature, enzymatically active heterodimer.|
|Cellular Location||Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Co-localizes with calnexin in the endoplasmic reticulum|
|Tissue Location||Highly expressed in fetal and adult kidney and liver|
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Provided below are standard protocols that you may find useful for product applications.
GGT2 initiates extracellular glutathione (GSH) breakdown; catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors (By similarity).
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