|Application ||WB, FC, E|
|Calculated MW||48548 Da|
|Antigen Region||361-390 aa|
|Other Names||Mitochondrial inner membrane protein OXA1L, Hsa, OXA1Hs, Oxidase assembly 1-like protein, OXA1-like protein, OXA1L|
|Target/Specificity||This OXA1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human OXA1L.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OXA1L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
OXA1L is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase.
Haque, M.E., et al. J. Biol. Chem. 285(45):34991-34998(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Haque, M.E., et al. J. Biol. Chem. 285(36):28353-28362(2010)
Sato, T., et al. J. Biol. Chem. 284(22):14819-14827(2009)
Stiburek, L., et al. J. Mol. Biol. 374(2):506-516(2007)
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