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NPTN Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NPTN Antibody (N-term) AP12852A
    NPTN Antibody (N-term) (Cat. #AP12852a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NPTN antibody detected the NPTN protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y639
Other Accession P97546, P97300, NP_001154835.1, NP_036560.1, NP_001154836.1, NP_059429.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44387 Da
Antigen Region 188-216 aa
Additional Information
Gene ID 27020
Other Names Neuroplastin, Stromal cell-derived receptor 1, SDR-1, NPTN, SDFR1, SDR1
Target/Specificity This NPTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the N-terminal region of human NPTN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNPTN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPTN
Synonyms SDFR1, SDR1
Function Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Enriched at postsynaptic density.
Tissue Location Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level) {ECO:0000269|PubMed:17196182, ECO:0000269|Ref.1}
Research Areas
Citations (0)

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Background

This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

References

Bernstein, H.G., et al. Brain Res. 1134(1):107-112(2007)
Saito, A., et al. Neurosci. Lett. 411(3):168-173(2007)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
Langnaese, K., et al. J. Biol. Chem. 272(2):821-827(1997)

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$ 295.00
$ 99.00
Cat# AP12852A
Size:
Quantity:
(40 western blots)
Availability: In Stock
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