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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PIK3AP1 Antibody (C-term)   

PIK3AP1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PIK3AP1 Antibody (C-term) AP12861b
    PIK3AP1 Antibody (C-term) (Cat. #AP12861b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PIK3AP1 antibody detected the PIK3AP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6ZUJ8
Other Accession NP_689522.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 90398 Da
Antigen Region 639-668 aa
Additional Information
Gene ID 118788
Other Names Phosphoinositide 3-kinase adapter protein 1, B-cell adapter for phosphoinositide 3-kinase, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, BCAP
Target/Specificity This PIK3AP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-668 amino acids from the C-terminal region of human PIK3AP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPIK3AP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PIK3AP1
Synonyms BCAP
Function Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein
Tissue Location Expressed in natural killer (NK) cells.
Research Areas
Citations (0)

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PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).


Koutros, S., et al. Cancer Res. 70(6):2389-2396(2010)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Maruoka, M., et al. FEBS Lett. 579(14):2986-2990(2005)
Okada, T., et al. Immunity 13(6):817-827(2000)

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$ 295.00
$ 99.00
Cat# AP12861b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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