|Application ||WB, E|
|Calculated MW||31670 Da|
|Antigen Region||256-285 aa|
|Other Names||SLAM family member 8, B-lymphocyte activator macrophage expressed, BCM-like membrane protein, CD353, SLAMF8, BLAME|
|Target/Specificity||This SLAMF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the C-terminal region of human SLAMF8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLAMF8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in lymph node, spleen, thymus and bone marrow.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
Tangye, S.G., et al. J. Immunol. 171(5):2485-2495(2003)
Kingsbury, G.A., et al. J. Immunol. 166(9):5675-5680(2001)
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