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SLAMF8 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SLAMF8 Antibody (C-term) AP12868b
    SLAMF8 Antibody (C-term) (Cat. #AP12868b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the SLAMF8 antibody detected the SLAMF8 protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9P0V8
Other Accession NP_064510.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 31670 Da
Antigen Region 256-285 aa
Additional Information
Gene ID 56833
Other Names SLAM family member 8, B-lymphocyte activator macrophage expressed, BCM-like membrane protein, CD353, SLAMF8, BLAME
Target/Specificity This SLAMF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the C-terminal region of human SLAMF8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLAMF8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLAMF8
Synonyms BLAME
Function May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Cellular Location Membrane; Single-pass type I membrane protein.
Tissue Location Expressed in lymph node, spleen, thymus and bone marrow.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
Tangye, S.G., et al. J. Immunol. 171(5):2485-2495(2003)
Kingsbury, G.A., et al. J. Immunol. 166(9):5675-5680(2001)

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$ 365.00
$ 140.00
Cat# AP12868b
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