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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GMPR Antibody (C-term)   

GMPR Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GMPR Antibody (C-term) AP12887b
    Western blot analysis of GMPR (arrow) using rabbit polyclonal GMPR Antibody (C-term) (Cat. #AP12887b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GMPR gene.
  • IHC-P - GMPR Antibody (C-term) AP12887b
    GMPR Antibody (C-term) (Cat. #AP12887b)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GMPR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P36959
Other Accession NP_006868.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37419 Da
Antigen Region 238-267 aa
Additional Information
Gene ID 2766
Other Names GMP reductase 1, Guanosine 5'-monophosphate oxidoreductase 1, Guanosine monophosphate reductase 1, GMPR, GMPR1
Target/Specificity This GMPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-267 amino acids from the C-terminal region of human GMPR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGMPR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GMPR1
Function Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Research Areas
Citations (0)

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This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.


Chasman, D.I., et al. PLoS Genet. 5 (11), E1000730 (2009) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Deng, Y., et al. Int. J. Biochem. Cell Biol. 34(9):1035-1050(2002)
Salvatore, D., et al. J. Biol. Chem. 273(47):31092-31096(1998)

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Cat# AP12887b
(40 western blots)
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