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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GCAT Antibody (N-term)   

GCAT Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GCAT Antibody (N-term) AP12897a
    Western blot analysis of GCAT (arrow) using rabbit polyclonal GCAT Antibody (N-term) (Cat. #AP12897a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GCAT gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75600
Other Accession Q0P5L8, NP_055106.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45285 Da
Antigen Region 101-128 aa
Additional Information
Gene ID 23464
Other Names 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase, GCAT, KBL
Target/Specificity This GCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-128 amino acids from the N-terminal region of human GCAT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGCAT Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KBL
Cellular Location Mitochondrion. Nucleus. Note=Translocates to the nucleus upon cold and osmotic stress
Tissue Location Strongly expressed in heart, brain, liver and pancreas. Also found in lung.
Research Areas
Citations (0)

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The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.


Jacquot, C., et al. Anticancer Res. 22(4):2229-2235(2002)
Edgar, A.J., et al. Eur. J. Biochem. 267(6):1805-1812(2000)
Tressel, T., et al. J. Biol. Chem. 261(35):16428-16437(1986)

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$ 295.00
$ 99.00
Cat# AP12897a
(40 western blots)
Availability: In Stock
Bulk Size
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