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CTBP2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P56545 |
| Other Accession | Q9W758, Q9EQH5, P56546, Q0VCQ1, NP_073713.2, NP_001320.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48945 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 1488 |
|---|---|
| Other Names | C-terminal-binding protein 2, CtBP2, CTBP2 |
| Target/Specificity | This CTBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CTBP2. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CTBP2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CTBP2 |
|---|---|
| Function | Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). |
| Cellular Location | Nucleus. Synapse. |
| Tissue Location | Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. [provided by RefSeq].
References
Bao, B.Y., et al. Clin. Chim. Acta 411 (17-18), 1232-1237 (2010) :
Liu, H., et al. Prostate (2010) In press :
Kim, S.T., et al. Prostate (2010) In press :
Gallagher, D.J., et al. Clin. Cancer Res. 16(10):2819-2832(2010)
Kitamura, F., et al. Int. Arch. Allergy Immunol. 152 SUPPL 1, 18-21 (2010) :
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