|Application ||WB, IHC-P, E|
|Other Accession||Q9W758, Q9EQH5, P56546, Q0VCQ1, NP_073713.2, NP_001320.1|
|Predicted||Bovine, Mouse, Rat, Xenopus|
|Calculated MW||48945 Da|
|Antigen Region||1-30 aa|
|Other Names||C-terminal-binding protein 2, CtBP2, CTBP2|
|Target/Specificity||This CTBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CTBP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CTBP2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).|
|Cellular Location||Nucleus. Cell junction, synapse|
|Tissue Location||Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. [provided by RefSeq].
Bao, B.Y., et al. Clin. Chim. Acta 411 (17-18), 1232-1237 (2010) :
Liu, H., et al. Prostate (2010) In press :
Kim, S.T., et al. Prostate (2010) In press :
Gallagher, D.J., et al. Clin. Cancer Res. 16(10):2819-2832(2010)
Kitamura, F., et al. Int. Arch. Allergy Immunol. 152 SUPPL 1, 18-21 (2010) :
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