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DGCR6L Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DGCR6L Antibody (Center) AP12911C
    Western blot analysis of DGCR6L (arrow) using rabbit polyclonal DGCR6L Antibody (Center) (Cat. #AP12911c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DGCR6L gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BY27
Other Accession Q14129, NP_150282.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24932 Da
Antigen Region 108-135 aa
Additional Information
Gene ID 85359
Other Names Protein DGCR6L, DiGeorge syndrome critical region 6-like protein, DGCR6L
Target/Specificity This DGCR6L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-135 amino acids from the Central region of human DGCR6L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDGCR6L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.
Cellular Location Nucleus. Note=Predominantly nuclear
Tissue Location Widely expressed in fetal and adult tissues. Highest expression in liver, heart and skeletal muscle. Lower levels in pancreas and placenta. Weak expression in brain
Research Areas
Citations (0)

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This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome.


Li, X., et al. Int. J. Biochem. Cell Biol. 42(1):70-79(2010)
Pfuhl, T., et al. Hum. Genet. 117(1):70-80(2005)
Edelmann, L., et al. Genome Res. 11(2):208-217(2001)

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Cat# AP12911C
(40 western blots)
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