FUT6 Antibody (N-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, WB, E |
---|---|
Primary Accession | P51993 |
Other Accession | NP_001035791.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Calculated MW | 41860 Da |
Antigen Region | 20-49 aa |
Gene ID | 2528 |
---|---|
Other Names | Alpha-(1, 3)-fucosyltransferase 6, Fucosyltransferase 6, Fucosyltransferase VI, Fuc-TVI, FucT-VI, Galactoside 3-L-fucosyltransferase, FUT6, FCT3A |
Target/Specificity | This FUT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human FUT6. |
Dilution | IHC-P~~1:10~50 WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FUT6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FUT6 |
---|---|
Synonyms | FCT3A |
Function | Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates. |
Cellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi |
Tissue Location | Kidney, liver, colon, small intestine, bladder, uterus and salivary gland |

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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Stern, H.M., et al. Clin. Cancer Res. 16(5):1587-1596(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Norden, R., et al. Glycobiology 19(7):776-788(2009)
Higai, K., et al. Glycoconj. J. 25(3):225-235(2008)

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