|Application ||WB, E|
|Calculated MW||52817 Da|
|Antigen Region||220-248 aa|
|Other Names||Matrilin-3, MATN3|
|Target/Specificity||This MATN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the Central region of human MATN3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MATN3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.|
|Tissue Location||Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Zintzaras, E., et al. Am. J. Epidemiol. 171(8):851-858(2010)
Otten, C., et al. Hum. Mutat. 31(3):254-263(2010)
Klatt, A.R., et al. FEBS Lett. 583(22):3611-3617(2009)
Vincourt, J.B., et al. Arthritis Rheum. 58(9):2798-2808(2008)
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