|Application ||WB, E|
|Calculated MW||12927 Da|
|Antigen Region||5-34 aa|
|Other Names||Interferon alpha-inducible protein 6, Interferon-induced protein 6-16, Ifi-6-16, IFI6, G1P3|
|Target/Specificity||This IFI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-34 amino acids from the N-terminal region of human IFI6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IFI6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Szegedi, K., et al. Exp. Dermatol. 19(3):269-278(2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Zhao, D., et al. Virol. J. 5, 114 (2008) :
Cheriyath, V., et al. J. Clin. Invest. 117(10):3107-3117(2007)
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