|Application ||WB, E|
|Other Accession||P59759, NP_054767.3|
|Calculated MW||118127 Da|
|Antigen Region||72-101 aa|
|Other Names||MKL/myocardin-like protein 2, Megakaryoblastic leukemia 2, Myocardin-related transcription factor B, MRTF-B, MKL2, KIAA1243, MRTFB|
|Target/Specificity||This MKL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human MKL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MKL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.|
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Provided below are standard protocols that you may find useful for product applications.
MKL2 acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.
Huang, D., et al. Genes Chromosomes Cancer 49(9):810-818(2010)
Holt, R., et al. Eur. J. Hum. Genet. 18(9):1013-1019(2010)
Medjkane, S., et al. Nat. Cell Biol. 11(3):257-268(2009)
Lagna, G., et al. J. Biol. Chem. 282(51):37244-37255(2007)
Morita, T., et al. J. Cell Biol. 179(5):1027-1042(2007)
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