|Application ||WB, IHC-P, E|
|Calculated MW||87811 Da|
|Antigen Region||671-700 aa|
|Other Names||GRIP and coiled-coil domain-containing protein 1, Golgi coiled-coil protein 1, GCC1|
|Target/Specificity||This GCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the C-terminal region of human GCC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GCC1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably involved in maintaining Golgi structure.|
|Cellular Location||Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq].
Lieu, Z.Z., et al. Mol. Biol. Cell 18(12):4979-4991(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Luke, M.R., et al. Biochem. J. 388 (PT 3), 835-841 (2005) :
Luke, M.R., et al. J. Biol. Chem. 278(6):4216-4226(2003)
Kjer-Nielsen, L., et al. Curr. Biol. 9(7):385-388(1999)
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