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GCC1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GCC1 Antibody (C-term) AP12984B
    GCC1 Antibody (C-term) (Cat. #AP12984b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GCC1 antibody detected the GCC1 protein (arrow).
    detail
  • IHC-P - GCC1 Antibody (C-term) AP12984B
    GCC1 Antibody (C-term) (Cat. #AP12984b)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GCC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q96CN9
Other Accession NP_078799.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 87811 Da
Antigen Region 671-700 aa
Additional Information
Gene ID 79571
Other Names GRIP and coiled-coil domain-containing protein 1, Golgi coiled-coil protein 1, GCC1
Target/Specificity This GCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the C-terminal region of human GCC1.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGCC1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GCC1
Function Probably involved in maintaining Golgi structure.
Cellular Location Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein
Research Areas
Citations (0)
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Background

The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq].

References

Lieu, Z.Z., et al. Mol. Biol. Cell 18(12):4979-4991(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Luke, M.R., et al. Biochem. J. 388 (PT 3), 835-841 (2005) :
Luke, M.R., et al. J. Biol. Chem. 278(6):4216-4226(2003)
Kjer-Nielsen, L., et al. Curr. Biol. 9(7):385-388(1999)

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$ 182.50
$ 70.00
Cat# AP12984B
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