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RASAL2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UJF2 |
| Other Accession | NP_004832.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 128558 Da |
| Antigen Region | 675-703 aa |
| Gene ID | 9462 |
|---|---|
| Other Names | Ras GTPase-activating protein nGAP, RAS protein activator-like 2, RASAL2, NGAP |
| Target/Specificity | This RASAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 675-703 amino acids from the Central region of human RASAL2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RASAL2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RASAL2 |
|---|---|
| Synonyms | NGAP |
| Function | Inhibitory regulator of the Ras-cyclic AMP pathway. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
References
Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)
Shibui, T., et al. Biotechnol. Lett. 30(12):2037-2043(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Noto, S., et al. FEBS Lett. 441(1):127-131(1998)
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