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PCDHB11 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP12988a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12988a-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
PCDHB11 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q9Y5F2 |
| Other Accession | NP_061754.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 87088 Da |
PCDHB11 Antibody (N-term) - Additional info | |
| Gene ID 56125 | |
| Other Names PCDHB11; Protocadherin beta-11 | |
| Target/Specificity This PCDHB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-76 amino acids from the N-terminal region of human PCDHB11. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions PCDHB11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
PCDHB11 Antibody (N-term) - Protein Information | |
| Name PCDHB11 | |
| Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain | |
| Cellular Location Cell membrane; Single-pass type I membrane protein (By similarity) | |
PCDHB11 Antibody (N-term) - Related products
PCDHB11 Antibody (N-term) - Application data
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PCDHB11 Antibody (N-term) (Cat. #AP12988a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PCDHB11 antibody detected the PCDHB11 protein (arrow).
PCDHB11 Antibody (N-term) - Research Areas
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BACKGROUND
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
REFERENCES
Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) : Frank, M., et al. Curr. Opin. Cell Biol. 14(5):557-562(2002) Vanhalst, K., et al. FEBS Lett. 495 (1-2), 120-125 (2001) : Wu, Q., et al. Genome Res. 11(3):389-404(2001) Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)
