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LARP7 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP12990b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12990b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
LARP7 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | Q4G0J3 |
| Other Accession | Q5XI01, Q05CL8, Q4R627, NP_056269.1, NP_057732.2 |
| Reactivity | Human |
| Predicted | Mouse, Monkey, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 66899 Da |
LARP7 Antibody (C-term) - Additional info | |
| Gene ID 51574 | |
| Other Names LARP7; La-related protein 7; La ribonucleoprotein domain family member 7; P-TEFb-interaction protein for 7SK stability | |
| Target/Specificity This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 526-556 amino acids from the C-terminal region of human LARP7. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions LARP7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
LARP7 Antibody (C-term) - Protein Information | |
| Name LARP7 | |
| Function Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation | |
| Cellular Location Nucleus, nucleoplasm. | |
LARP7 Antibody (C-term) - Related products
LARP7 Antibody (C-term) - Application data
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LARP7 Antibody (C-term) (Cat. #AP12990b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the LARP7 antibody detected the LARP7 protein (arrow).
LARP7 Antibody (C-term) - Research Areas
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BACKGROUND
LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
REFERENCES
Tyagi, M., et al. J. Virol. 84(13):6425-6437(2010) Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010) Markert, A., et al. EMBO Rep. 9(6):569-575(2008) Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008) He, N., et al. Mol. Cell 29(5):588-599(2008)
