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LARP7 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # SizeAvailability Price  
AP12990b 400 µl
(40 western blots)
In Stock
$ 265.00email & fax$ 251.75online
Add to cart
AP12990b-ev 80 µl
(8 western blots)
In Stock
$ 95.00email & fax$ 90.25online
Add to cart
  • Specification
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LARP7 Antibody (C-term) - Product info

Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary AccessionQ4G0J3
Other AccessionQ5XI01, Q05CL8, Q4R627, NP_056269.1, NP_057732.2
ReactivityHuman
PredictedMouse, Rat, Monkey
Isotype Rabbit Ig
Calculated MW 66899 Da

LARP7 Antibody (C-term) - Additional info

Gene ID 51574
Other Names
LARP7; La-related protein 7; La ribonucleoprotein domain family member 7; P-TEFb-interaction protein for 7SK stability
Target/Specificity
This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human LARP7.
Dilution
WB~~1:1000
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
LARP7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

LARP7 Antibody (C-term) - Protein Information

Name LARP7
Function
Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Cellular Location
Nucleus, nucleoplasm.

LARP7 Antibody (C-term) - Related products

BP12990b: LARP7 Antibody (C-term) Blocking Peptides

LARP7 Antibody (C-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

REFERENCES

Tyagi, M., et al. J. Virol. 84(13):6425-6437(2010)
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Markert, A., et al. EMBO Rep. 9(6):569-575(2008)
Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)
He, N., et al. Mol. Cell 29(5):588-599(2008)