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LARP7 Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
United StatesOrdering Information
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(40 western blots)
|In Stock||$ 265.00||DISCONTINUED INQUIRE CLICK INQUIRE Add to cart|
(8 western blots)
|In Stock||$ 95.00||DISCONTINED INQUIRE CLICK INQUIRE Add to cart|
- Citations : 0
LARP7 Antibody (C-term) - Product Information
|Other Accession||Q5XI01, Q05CL8, Q4R627, NP_056269.1, NP_057732.2|
|Predicted||Monkey, Mouse, Rat|
|Calculated MW||66899 Da|
|Antigen Region||527-556 aa|
LARP7 Antibody (C-term) - Additional Information
|Gene ID 51574|
LARP7; La-related protein 7; La ribonucleoprotein domain family member 7; P-TEFb-interaction protein for 7SK stability
This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human LARP7.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
LARP7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
LARP7 Antibody (C-term) - Protein Information
Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
LARP7 Antibody (C-term) - Related Products
LARP7 Antibody (C-term) - Research Areas
LARP7 Antibody (C-term) (Cat. #AP12990b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the LARP7 antibody detected the LARP7 protein (arrow).
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Provided below are standard protocols that you may find useful for product applications.
LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Tyagi, M., et al. J. Virol. 84(13):6425-6437(2010)
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Markert, A., et al. EMBO Rep. 9(6):569-575(2008)
Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)
He, N., et al. Mol. Cell 29(5):588-599(2008)