|Application ||WB, E|
|Calculated MW||54166 Da|
|Antigen Region||201-230 aa|
|Other Names||Galactose-3-O-sulfotransferase 4, Gal3ST-4, 282-, Beta-galactose-3-O-sulfotransferase 4, Gal-beta-1, 3-GalNAc 3'-sulfotransferase, GAL3ST4|
|Target/Specificity||This GAL3ST4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human GAL3ST4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GAL3ST4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transfer of sulfate to beta-1,3-linked galactose residues in O-linked glycoproteins. Good substrates include asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed mainly in placenta, thymus, testis, ovary, spinal cord, trachea and adrenal gland and at low levels in brain, lung, spleen, prostate, small intestine, colon, stomach thyroid and lymph node.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates.
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Chandrasekaran, E.V., et al. J. Biol. Chem. 279(11):10032-10041(2004)
Seko, A., et al. J. Biol. Chem. 276(28):25697-25704(2001)
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