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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BVES Antibody (C-term)   

BVES Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BVES Antibody (C-term) AP13010b
    BVES Antibody (C-term) (Cat. #AP13010b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BVES antibody detected the BVES protein (arrow).
  • IHC-P - BVES Antibody (C-term) AP13010b
    BVES Antibody (C-term) (Cat. #AP13010b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BVES Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NE79
Other Accession NP_009004.2, NP_671488.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41451 Da
Antigen Region 313-342 aa
Additional Information
Gene ID 11149
Other Names Blood vessel epicardial substance, hBVES, Popeye domain-containing protein 1, Popeye protein 1, BVES, POP1, POPDC1
Target/Specificity This BVES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the C-terminal region of human BVES.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBVES Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms POP1, POPDC1
Function Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3- mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.
Cellular Location Lateral cell membrane. Cell junction, tight junction. Membrane; Multi-pass membrane protein. Note=Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity) Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells.
Tissue Location Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle
Research Areas
Citations (0)

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This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Two transcript variants encoding the same protein have been found for this gene.


Kim, M., et al. Carcinogenesis 31(9):1685-1693(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Sulem, P., et al. Nat. Genet. 41(6):734-738(2009)
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Feng, Q., et al. Cancer Epidemiol. Biomarkers Prev. 17(3):645-654(2008)

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$ 295.00
$ 99.00
Cat# AP13010b
(40 western blots)
Availability: In Stock
Bulk Size
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