|Application ||WB, IHC-P, E|
|Calculated MW||28969 Da|
|Antigen Region||231-260 aa|
|Other Names||Transmembrane protein 70, mitochondrial, TMEM70|
|Target/Specificity||This TMM70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human TMM70.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMM70 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in biogenesis of mitochondrial ATP synthase.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene likely encodes a mitochondrial membrane protein. The encoded protein may play a role in biogenesis of mitochondrial ATP synthase. Mutations in this gene have been associated with neonatal mitochondrial encephalocardiomyopathy due to ATP synthase deficiency. Alternatively spliced transcript variants have been described.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Karasik, D., et al. J. Bone Miner. Res. 25(7):1555-1563(2010)
Honzik, T., et al. Arch. Dis. Child. 95(4):296-301(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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