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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ARHGAP22 Antibody (C-term)   

ARHGAP22 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ARHGAP22 Antibody (C-term) AP13013b
    ARHGAP22 Antibody (C-term) (Cat. #AP13013b) western blot analysis in MDA-MB231,WiDr,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ARHGAP22 antibody detected the ARHGAP22 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z5H3
Other Accession NP_067049.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76779 Da
Antigen Region 604-633 aa
Additional Information
Gene ID 58504
Other Names Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2
Target/Specificity This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-633 amino acids from the C-terminal region of human ARHGAP22.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARHGAP22 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RHOGAP2
Function Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Mainly cytoplasmic. Some fraction is nuclear (By similarity).
Research Areas
Citations (0)

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ARHGAPs, such as ARHGAP22, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Dick, D.M., et al. Mol. Psychiatry (2010) In press :
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Katoh, M., et al. Int. J. Mol. Med. 14(2):333-338(2004)

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Cat# AP13013b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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