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ARHGAP22 Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
United StatesOrdering Information
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(40 western blots)
|In Stock||$ 265.00||DISCONTINUED INQUIRE CLICK INQUIRE Add to cart|
(8 western blots)
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- Citations : 0
ARHGAP22 Antibody (C-term) - Product Information
|Calculated MW||76779 Da Da|
|Antigen Region||604-633 aa|
ARHGAP22 Antibody (C-term) - Additional Information
|Gene ID 58504|
Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2
This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-633 amino acids from the C-terminal region of human ARHGAP22.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ARHGAP22 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
ARHGAP22 Antibody (C-term) - Protein Information
Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).
Cytoplasm. Nucleus. Note=Mainly cytoplasmic. Some fraction is nuclear (By similarity).
ARHGAP22 Antibody (C-term) - Related Products
ARHGAP22 Antibody (C-term) - Research Areas
ARHGAP22 Antibody (C-term) (Cat. #AP13013b) western blot analysis in MDA-MB231,WiDr,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ARHGAP22 antibody detected the ARHGAP22 protein (arrow).
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Provided below are standard protocols that you may find useful for product applications.
ARHGAPs, such as ARHGAP22, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Dick, D.M., et al. Mol. Psychiatry (2010) In press :
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Katoh, M., et al. Int. J. Mol. Med. 14(2):333-338(2004)