|Application ||WB, FC, E|
|Other Accession||Q9ESX2, NP_954871.1|
|Calculated MW||39840 Da|
|Antigen Region||196-225 aa|
|Other Names||Transcription factor Sp6, Krueppel-like factor 14, SP6, KLF14|
|Target/Specificity||This SP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the Central region of human SP6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SP6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes cell proliferation.|
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Provided below are standard protocols that you may find useful for product applications.
SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).
Nakamura, T., et al. J. Biol. Chem. 279(1):626-634(2004)
Scohy, S., et al. Genomics 70(1):93-101(2000)
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