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DUX4 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DUX4 Antibody (C-term) AP13022B
    DUX4 Antibody (C-term) (Cat. #AP13022b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the DUX4 antibody detected the DUX4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBX2
Other Accession P0CJ90, P0CJ89, P0CJ88, P0CJ87, P0CJ86, P0CJ85
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44940 Da
Antigen Region 376-404 aa
Additional Information
Gene ID 100288687
Other Names Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}, Double homeobox protein 10 {ECO:0000312|EMBL:AAK915091}, DUX4 (HGNC:50800), DUX10
Target/Specificity This DUX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human DUX4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDUX4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUX4 (HGNC:50800)
Synonyms DUX10
Function Involved in transcriptional regulation. May regulate microRNA (miRNA) expression.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:15709750, ECO:0000269|PubMed:21060811}. Note=Actively transported through the nuclear pore complex (NPC)
Tissue Location Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level) (PubMed:21060811). Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells
Research Areas
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DUX4 may be involved in transcriptional regulation.

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Cat# AP13022B
(40 western blots)
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