|Application ||WB, E|
|Calculated MW||21081 Da|
|Antigen Region||1-30 aa|
|Other Names||Phosphatidylinositol N-acetylglucosaminyltransferase subunit H, Phosphatidylinositol-glycan biosynthesis class H protein, PIG-H, PIGH|
|Target/Specificity||This PIGH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PIGH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PIGH Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Kinoshita, T., et al. Curr Opin Chem Biol 4(6):632-638(2000)
Watanabe, R., et al. EMBO J. 17(4):877-885(1998)
Watanabe, R., et al. J. Biol. Chem. 271(43):26868-26875(1996)
Ware, R.E., et al. Blood 83(12):3753-3757(1994)
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