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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CTPS2 Antibody (C-term)   

CTPS2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CTPS2 Antibody (C-term) AP13030b
    CTPS2 Antibody (C-term) (Cat. #AP13030b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CTPS2 antibody detected the CTPS2 protein (arrow).
  • WB - CTPS2 Antibody (C-term) AP13030b
    Western blot analysis of CTPS2 (arrow) using rabbit polyclonal CTPS2 Antibody (C-term) (Cat. #AP13030b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CTPS2 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NRF8
Other Accession Q1RMS2, NP_787055.1, NP_062831.3
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 65678 Da
Antigen Region 450-479 aa
Additional Information
Gene ID 56474
Other Names CTP synthase 2, CTP synthetase 2, UTP--ammonia ligase 2, CTPS2
Target/Specificity This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human CTPS2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTPS2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTPS2
Function Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
Research Areas
Citations (0)

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The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.


Kassel, K.M., et al. J. Biol. Chem. 285(44):33727-33736(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Han, G.S., et al. J. Biol. Chem. 280(46):38328-38336(2005)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
van Kuilenburg, A.B., et al. Biochim. Biophys. Acta 1492 (2-3), 548-552 (2000) :

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$ 295.00
$ 99.00
Cat# AP13030b
(40 western blots)
Availability: In Stock
Bulk Size
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