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TOR1B Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | O14657 |
| Other Accession | NP_055321.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37979 Da |
| Antigen Region | 215-243 aa |
| Gene ID | 27348 |
|---|---|
| Other Names | Torsin-1B, Torsin ATPase-1B, 364-, Torsin family 1 member B, TOR1B, DQ1 |
| Target/Specificity | This TOR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human TOR1B. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TOR1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TOR1B |
|---|---|
| Synonyms | DQ1 |
| Function | May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non- neural cells nuclear envelope and endoplasmic reticulum integrity. May have a redundant function with TOR1A in non-neural tissues. |
| Cellular Location | Endoplasmic reticulum lumen. Nucleus membrane |
| Tissue Location | Widely expressed with low levels in brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TOR1B may serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins (By similarity).
References
Sharma, N., et al. Mov. Disord. (2010) In press :
Kamm, C., et al. Neurology 67(10):1857-1859(2006)
Bahn, E., et al. Brain Res. 1116(1):112-119(2006)
Hewett, J.W., et al. J. Neurochem. 89(5):1186-1194(2004)
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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