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ARPP-21 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ARPP-21 Antibody (N-term) AP13040A
    ARPP-21 Antibody (N-term) (Cat. #AP13040a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ARPP-21 antibody detected the ARPP-21 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UBL0
Other Accession Q9DCB4, NP_001020239.1, NP_001020240.1, NP_938409.1, NP_057384.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 89196 Da
Antigen Region 85-114 aa
Additional Information
Gene ID 10777
Other Names cAMP-regulated phosphoprotein 21, ARPP-21, Thymocyte cAMP-regulated phosphoprotein, ARPP21, TARPP
Target/Specificity This ARPP-21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human ARPP-21.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARPP-21 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARPP21
Synonyms TARPP
Function Isoform 2 may act as a competitive inhibitor of calmodulin- dependent enzymes such as calcineurin in neurons.
Cellular Location Cytoplasm.
Tissue Location Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level)
Research Areas
Citations (0)
citation

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Background

Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons (By similarity).

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Brill, L.M., et al. Anal. Chem. 76(10):2763-2772(2004)
Brill, L.M., et al. Anal. Chem. 76(10):2763-2772(2004)

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$ 182.50
$ 70.00
Cat# AP13040A
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