|Application ||WB, IHC-P, FC, E|
|Other Accession||NP_001020368.1, NP_001020370.1|
|Calculated MW||43501 Da|
|Antigen Region||22-50 aa|
|Other Names||Chitinase-3-like protein 2, Chondrocyte protein 39, YKL-39, CHI3L2|
|Target/Specificity||This CHI3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human CHI3L2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CHI3L2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.|
|Tissue Location||Highest expression in chondrocytes, followed by synoviocytes, lung and heart. Not detected in spleen, pancreas, and liver. May also be expressed in developing brain and placenta|
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Provided below are standard protocols that you may find useful for product applications.
CHI3L2 may bind glycan structure with high affinity, but not heparin. Has no chitotriosidase activity.
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Steck, E., et al. Biochem. Biophys. Res. Commun. 299(1):109-115(2002)
Hu, B., et al. J. Biol. Chem. 271(32):19415-19420(1996)
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