|Application ||WB, IF, FC, E|
|Calculated MW||66152 Da|
|Antigen Region||406-434 aa|
|Other Names||MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3, MPP3, DLG3|
|Target/Specificity||This MPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-434 amino acids from the C-terminal region of human MPP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MPP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein.
Qin, L., et al. Zhonghua Gan Zang Bing Za Zhi 15(7):509-512(2007)
Kantardzhieva, A., et al. FEBS J. 273(6):1152-1165(2006)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Fukuhara, H., et al. Oncogene 22(40):6160-6165(2003)
Shin, B.K., et al. J. Biol. Chem. 278(9):7607-7616(2003)
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