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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   GNLY Antibody (N-term)   

GNLY Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GNLY Antibody (N-term) AP13075a
    GNLY Antibody (N-term) (Cat. #AP13075a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GNLY antibody detected the GNLY protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22749
Other Accession NP_006424.2, NP_036615.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 16374 Da
Antigen Region 14-42 aa
Additional Information
Gene ID 10578
Other Names Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519
Target/Specificity This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNLY Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LAG2, NKG5, TLA519
Function Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.
Cellular Location Secreted. Note=Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation
Tissue Location Expressed in natural killer and T-cells.
Research Areas
Citations (0)

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The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.


Xing, J., et al. J. Immunol. 185(9):5074-5081(2010)
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Yang, C., et al. Int. J. Tuberc. Lung Dis. 13(11):1360-1366(2009)
Hogg, A.E., et al. J. Leukoc. Biol. 86(5):1191-1203(2009)

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$ 295.00
$ 99.00
Cat# AP13075a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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