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WDR12 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - WDR12 Antibody (Center) AP13076c
    WDR12 Antibody (Center) (Cat. #AP13076c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the WDR12 antibody detected the WDR12 protein (arrow).
  • IHC-P - WDR12 Antibody (Center) AP13076c
    WDR12 Antibody (Center) (Cat. #AP13076c)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WDR12 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9GZL7
Other Accession Q0VC24, NP_060726.3
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47708 Da
Antigen Region 210-239 aa
Additional Information
Gene ID 55759
Other Names Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}, WD repeat-containing protein 12 {ECO:0000255|HAMAP-Rule:MF_03029}, WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}
Target/Specificity This WDR12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human WDR12.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWDR12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}
Function Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Cellular Location Nucleus, nucleolus. Nucleus, nucleoplasm.
Citations (0)

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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.


Kathiresan, S., et al. Nat. Genet. 41(3):334-341(2009)
Rohrmoser, M., et al. Mol. Cell. Biol. 27(10):3682-3694(2007)
Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
Grimm, T., et al. Nucleic Acids Res. 34(10):3030-3043(2006)
Holzel, M., et al. J. Cell Biol. 170(3):367-378(2005)

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$ 295.00
$ 99.00
Cat# AP13076c
(40 western blots)
Availability: In Stock
Bulk Size
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