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RRAGC Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RRAGC Antibody (Center) AP13084c
    RRAGC Antibody (Center) (Cat. #AP13084c) western blot analysis in 293,MDA-MB231,Hela,HepG2 cell line lysates (35ug/lane).This demonstrates the RRAGC antibody detected the RRAGC protein (arrow).
  • IHC-P - RRAGC Antibody (Center) AP13084c
    RRAGC Antibody (Center) (Cat. #AP13084c)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RRAGC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HB90
Other Accession Q7TT45, Q9NQL2, Q99K70, NP_071440.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44224 Da
Antigen Region 169-198 aa
Additional Information
Gene ID 64121
Other Names Ras-related GTP-binding protein C, Rag C, RagC, GTPase-interacting protein 2, TIB929, RRAGC (HGNC:19902)
Target/Specificity This RRAGC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RRAGC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRRAGC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RRAGC (HGNC:19902)
Function Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.
Cellular Location Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA
Research Areas
Citations (0)

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RRAGC is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.


Sekiguchi, T., et al. J. Biol. Chem. 279(9):8343-8350(2004)
Sekiguchi, T., et al. J. Biol. Chem. 276(10):7246-7257(2001)
Horwitz, M.S. Virology 279(1):1-8(2001)

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Cat# AP13084c
(40 western blots)
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