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>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   SPT19 Antibody (C-term)   

SPT19 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SPT19 Antibody (C-term) AP13095b
    SPT19 Antibody (C-term) (Cat. #AP13095b) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the SPT19 antibody detected the SPT19 protein (arrow).
  • IHC-P - SPT19 Antibody (C-term) AP13095b
    SPT19 Antibody (C-term) (Cat. #AP13095b)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SPT19 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q7Z5L4
Other Accession NP_777587.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 122-150 aa
Additional Information
Other Names Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein, Spergen-1, SPATA19, SPERGEN1
Target/Specificity This SPT19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-150 amino acids from the C-terminal region of human SPT19.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPT19 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPATA19
Synonyms SPERGEN1
Function May have a role in spermiogenesis.
Cellular Location Mitochondrion outer membrane.
Tissue Location Expressed specifically in testis. EMBL; AF521713; AAP80739.1; -; mRNA EMBL; AK098717; BAC05390.1; -; mRNA EMBL; BC058039; AAH58039.1; -; mRNA CCDS; CCDS8493.1; - RefSeq; NP_001278921.1; NM_001291992.1 RefSeq; NP_777587.1; NM_174927.2 UniGene; Hs.97541; - ProteinModelPortal; Q7Z5L4; - SMR; Q7Z5L4; - BioGrid; 128597; 5 STRING; 9606.ENSP00000299140; - iPTMnet; Q7Z5L4; - PhosphoSitePlus; Q7Z5L4; - BioMuta; SPATA19; - PaxDb; Q7Z5L4; - PeptideAtlas; Q7Z5L4; - PRIDE; Q7Z5L4; - DNASU; 219938; - Ensembl; ENST00000299140; ENSP00000299140; ENSG00000166118 Ensembl; ENST00000532889; ENSP00000435248; ENSG00000166118 GeneID; 219938; - KEGG; hsa:219938; - UCSC; uc001qgv.2; human CTD; 219938; - DisGeNET; 219938; - GeneCards; SPATA19; - HGNC; HGNC:30614; SPATA19 HPA; HPA040082; - MIM; 609805; gene neXtProt; NX_Q7Z5L4; - OpenTargets; ENSG00000166118; - PharmGKB; PA142670884; - eggNOG; ENOG410IX9F; Eukaryota eggNOG; ENOG4111CPH; LUCA GeneTree; ENSGT00390000002749; - HOGENOM; HOG000154400; - HOVERGEN; HBG093991; - InParanoid; Q7Z5L4; - OMA; QHWLKKT; - OrthoDB; EOG091G0TH2; - PhylomeDB; Q7Z5L4; - TreeFam; TF337965; - GenomeRNAi; 219938; - PRO; PR:Q7Z5L4; - Proteomes; UP000005640; Chromosome 11 Bgee; ENSG00000166118; - CleanEx; HS_SPATA19; - ExpressionAtlas; Q7Z5L4; baseline and differential Genevisible; Q7Z5L4; HS GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW GO; GO:0007275; P:multicellular organism development; IEA:UniProtKB-KW GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW InterPro; IPR028219; SPATA19 Pfam; PF15212; SPATA19; 2 2: Evidence at transcript level; Complete proteome; Developmental protein; Differentiation; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Polymorphism; Reference proteome; Spermatogenesis; Transit peptide TRANSIT 1 24 Mitochondrion. CHAIN 25 167 Spermatogenesis-associated protein 19, mitochondrial /FTId=PRO_0000251609 MOD_RES 26 26 Phosphoserine {ECO:0000250|UniProtKB:Q920Q3} MOD_RES 129 129 Phosphoserine {ECO:0000250|UniProtKB:Q920Q3} VARIANT 50 50 A -> V (in dbSNP:rs2282602) /FTId=VAR_027697 SEQUENCE 167 AA; 19186 MW; 4FBEFCD966887FEB CRC64; MIITTWIVYI LARKGVGLPF LPITSSDIDV VESEAVSVLH HWLKKTEEEA SRGIKEKLSI NHPSQGVREK MSTDSPPTHG QDIHVTRDVV KHHLSKSDLL ANQSQEVLEE RTRIQFIRWS HTRIFQVPSE MTEDIMRDRI EQVRRSISRL TDVSAQDFSM RPSSSDC
Research Areas
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Background

SPT19 may have a role in spermiogenesis.

References

Ghafouri-Fard, S., et al. Br. J. Dermatol. 162(4):772-779(2010)
Stolk, L., et al. Nat. Genet. 41(6):645-647(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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Cat# AP13095b
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