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ORC5L Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ORC5L Antibody (Center) AP13101c
    ORC5L Antibody (Center) (Cat. #AP13101c) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the ORC5L antibody detected the ORC5L protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43913
Other Accession NP_002544.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50283 Da
Antigen Region 227-256 aa
Additional Information
Gene ID 5001
Other Names Origin recognition complex subunit 5, ORC5, ORC5L
Target/Specificity This ORC5L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human ORC5L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsORC5L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ORC5
Synonyms ORC5L
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication.
Cellular Location Nucleus.
Tissue Location Abundant in spleen, ovary, prostate, testis, and colon mucosa.
Citations (0)

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The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].


Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Siddiqui, K., et al. J. Biol. Chem. 282(44):32370-32383(2007)
Clarke, C.A., et al. Biochem. J. 388 (PT 2), 705-712 (2005) :
Volkening, M., et al. Mol. Cell. Biol. 25(4):1560-1568(2005)

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$ 295.00
$ 99.00
Cat# AP13101c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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