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RASD1 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP13102b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13102b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
RASD1 Antibody (C-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q9Y272 |
| Other Accession | NP_057168.1 |
| Reactivity | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 31642 Da |
RASD1 Antibody (C-term) - Additional info | |
| Gene ID 51655 | |
| Other Names RASD1; AGS1; DEXRAS1; Dexamethasone-induced Ras-related protein 1; Activator of G-protein signaling 1 | |
| Target/Specificity This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-278 amino acids from the C-terminal region of human RASD1. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RASD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RASD1 Antibody (C-term) - Protein Information | |
| Name RASD1 | |
| Synonyms AGS1, DEXRAS1 | |
| Function Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity) | |
| Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Cytoplasm, perinuclear region (By similarity) Nucleus (By similarity) | |
| Tissue Location Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues | |
RASD1 Antibody (C-term) - Related products
RASD1 Antibody (C-term) - Application data
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RASD1 Antibody (C-term) (Cat. #AP13102b) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RASD1 antibody detected the RASD1 protein (arrow).
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RASD1 Antibody (C-term) (Cat. #AP13102b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RASD1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
RASD1 Antibody (C-term) - Research Areas
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BACKGROUND
This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.
REFERENCES
Nojima, M., et al. Clin. Cancer Res. 15(13):4356-4364(2009) Lau, K.F., et al. J. Biol. Chem. 283(50):34728-34737(2008) Attarzadeh-Yazdi, G., et al. Neurochem. Res. 33(4):609-613(2008) Cheng, H.Y., et al. J. Neurosci. 26(50):12984-12995(2006) Nguyen, C.H., et al. Mol. Pharmacol. 69(5):1763-1771(2006)
