RPP25 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9BUL9 |
Other Accession | NP_060263.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 20632 Da |
Antigen Region | 169-197 aa |
Gene ID | 54913 |
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Other Names | Ribonuclease P protein subunit p25, RNase P protein subunit p25, RPP25 |
Target/Specificity | This RPP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the C-terminal region of human RPP25. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RPP25 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RPP25 |
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Function | Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:12003489, PubMed:16723659, PubMed:30454648). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465). |
Cellular Location | Nucleus, nucleolus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP. This subunit binds to RNA.
References
Hands-Taylor, K.L., et al. Nucleic Acids Res. 38(12):4052-4066(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Welting, T.J., et al. Nucleic Acids Res. 32(7):2138-2146(2004)
Guerrier-Takada, C., et al. RNA 8(3):290-295(2002)
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