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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PFDN5 Antibody (Center)   

PFDN5 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PFDN5 Antibody (Center) AP13122C
    PFDN5 Antibody (Center) (Cat. #AP13122c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PFDN5 antibody detected the PFDN5 protein (arrow).
  • WB - PFDN5 Antibody (Center) AP13122C
    PFDN5 Antibody (Center) (Cat. #AP13122c) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PFDN5 antibody detected the PFDN5 protein (arrow).
  • IHC-P - PFDN5 Antibody (Center) AP13122C
    PFDN5 Antibody (Center) (Cat. #AP13122c)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PFDN5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99471
Other Accession Q9WU28, Q8HYI9, NP_002615.2
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 17328 Da
Antigen Region 79-108 aa
Additional Information
Gene ID 5204
Other Names Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1, PFDN5, MM1, PFD5
Target/Specificity This PFDN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the Central region of human PFDN5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPFDN5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PFDN5
Synonyms MM1, PFD5
Function Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Cellular Location Isoform 1: Nucleus. Isoform 3: Nucleus.
Tissue Location Highly expressed in pancreas and skeletal muscle and moderately in other tissues
Research Areas
Citations (0)

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This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].


Ma, H.C., et al. J. Biomed. Sci. 15(4):417-425(2008)
Yoshida, T., et al. Exp. Cell Res. 314(6):1217-1228(2008)
Lubyova, B., et al. J. Biol. Chem. 282(44):31944-31953(2007)
Hagio, Y., et al. J. Cell. Biochem. 97(1):145-155(2006)
Bruneel, A., et al. Proteomics 5(15):3876-3884(2005)

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$ 295.00
$ 99.00
Cat# AP13122C
(40 western blots)
Availability: In Stock
Bulk Size
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