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RARRES1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RARRES1 Antibody (C-term) AP13138b
    RARRES1 Antibody (C-term) (Cat. #AP13138b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RARRES1 antibody detected the RARRES1 protein (arrow).
    detail
  • IHC-P - RARRES1 Antibody (C-term) AP13138b
    RARRES1 Antibody (C-term) (Cat. #AP13138b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RARRES1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession P49788
Other Accession NP_002879.2, NP_996846.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 33285 Da
Antigen Region 134-163 aa
Additional Information
Gene ID 5918
Other Names Retinoic acid receptor responder protein 1, Phorbol ester-induced gene 1 protein, PERG-1, RAR-responsive protein TIG1, Tazarotene-induced gene 1 protein, RARRES1, PEIG1, TIG1
Target/Specificity This RARRES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the C-terminal region of human RARRES1.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRARRES1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RARRES1
Synonyms PEIG1, TIG1
Function Inhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle.
Cellular Location Membrane; Single- pass type III membrane protein. Secreted
Tissue Location Detected in urine (at protein level).
Research Areas
Citations (0)
citation

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Background

This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.

References

Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Kwok, W.K., et al. Cancer Genet. Cytogenet. 194(1):58-64(2009)
Ohnishi, S., et al. Cell Prolif. 42(3):309-316(2009)
Son, M.S., et al. Oncol. Res. 17 (11-12), 571-580 (2009) :
Shutoh, M., et al. Cancer 104(8):1609-1619(2005)

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$ 182.50
$ 70.00
Cat# AP13138b
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