|Application ||WB, E|
|Calculated MW||67751 Da|
|Antigen Region||411-440 aa|
|Other Names||Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3, Polypeptide GalNAc transferase-like protein 3, GalNAc-T-like protein 3, pp-GaNTase-like protein 3, Protein-UDP acetylgalactosaminyltransferase-like protein 3, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3, Williams-Beuren syndrome chromosomal region 17 protein, WBSCR17, GALNTL3|
|Target/Specificity||This WBSCR17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-440 amino acids from the C-terminal region of human WBSCR17.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||WBSCR17 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Highly expressed in brain and heart. Weakly expressed in kidney, liver, lung and spleen|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an N-acetylgalactosaminyltransferase, which has 97% sequence identity to the mouse protein. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq].
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Nakamura, N., et al. Biol. Pharm. Bull. 28(3):429-433(2005)
Merla, G., et al. Hum. Genet. 110(5):429-438(2002)
Valero, M.C., et al. Genomics 69(1):1-13(2000)
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