|Application ||WB, E|
|Other Accession||Q9UEU5, Q4V326, Q6NT46, NP_001463.1|
|Calculated MW||12786 Da|
|Antigen Region||1-30 aa|
|Other Names||G antigen 2B/2C, GAGE-2B, GAGE-2C, Cancer/testis antigen 42, CT42, G antigen 2C, GAGE2B, GAGE2|
|Target/Specificity||This GAGE2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GAGE2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GAGE2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes.|
|Tissue Location||Expressed in a variety of tumor tissues but not in normal tissues, except testis|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq].
Sun, F., et al. Mol. Cancer Ther. 8(12):3191-3202(2009)
Gjerstorff, M.F., et al. Tissue Antigens 71(3):187-192(2008)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
De Backer, O., et al. Cancer Res. 59(13):3157-3165(1999)
Scarcella, D.L., et al. Clin. Cancer Res. 5(2):335-341(1999)
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