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B3GNT1 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # Size Availability Price  
AP13200b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP13200b-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
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B3GNT1 Antibody (C-term) - Product info

ApplicationWB, IHC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionO43505
Other AccessionQ5EA01, NP_006867.1
ReactivityHuman
PredictedBovine
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW47119 Da

B3GNT1 Antibody (C-term) - Additional info

Gene ID 11041
Other Names
B3GNT1; B3GNT6; N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase; I-beta-1, 3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 1
Target/Specificity
This B3GNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-394 amino acids from the C-terminal region of human B3GNT1.
Dilution
WB~~1:100~500
IHC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
B3GNT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

B3GNT1 Antibody (C-term) - Protein Information

Name B3GNT1
Synonyms B3GNT6
Function
Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location
In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser extent in placenta, pancreas, spleen, prostate, testis, ovary, small intestine and colon. Very weak expression in lung, liver, thymus and peripheral blood leukocytes. In fetal highly expressed in brain and kidney and to a lesser extent in lung and liver

B3GNT1 Antibody (C-term) - Related products

AP13200b: B3GNT1 Antibody (C-term)

DC05152: Human B3GNT1 cDNA Clone

B3GNT1 Antibody (C-term) - Application data

  • B3GNT1 Antibody (C-term) (Cat. #AP13200b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the B3GNT1 antibody detected the B3GNT1 protein (arrow).

  • B3GNT1 Antibody (C-term) (Cat. #AP13200b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of B3GNT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

B3GNT1 Antibody (C-term) - Research Areas

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BACKGROUND

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen.

REFERENCES

Bao, X., et al. Proc. Natl. Acad. Sci. U.S.A. 106(29):12109-12114(2009) Lee, P.L., et al. Glycobiology 19(6):655-664(2009) Sasaki, K., et al. Proc. Natl. Acad. Sci. U.S.A. 94(26):14294-14299(1997)