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> home > Products > Antibodies > Biological Process > Metabolic Process > ACSS2 Antibody (Center)

ACSS2 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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Catalog #	Size	Availability	Price
AP13231c	0.1 mg 400 ul	In Stock	$ 255.00	DISCONTINED INQUIRE CLICK INQUIRE Add to cart
AP13231c-ev20	20 ug 100 ul	In Stock	$ 95.00	DISCONTINED INQUIRE CLICK INQUIRE Add to cart

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ACSS2 Antibody (Center) - Product info
Application	WB, IHC Applications Legend: W=Western Blotting IP=Immunoprecipitation IHC-P=Immunohistochemistry (Paraffin) IF-IC=Immunofluorescence (Immunocytochemistry) F=Flow Cytometry
Primary Accession	Q9NR19
Other Accession	NP_061147.1
Reactivity	Human
Concentration	0.25 mg/ml
Isotype	Rabbit Ig
Calculated MW	78580 Da
ACSS2 Antibody (Center) - Additional info
Gene ID 55902
Other Names ACSS2; ACAS2; Acetyl-coenzyme A synthetase, cytoplasmic; Acetate--CoA ligase; Acetyl-CoA synthetase; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme
Target/Specificity This ACSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-290 amino acids from the Central region of human ACSS2.
Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions ACSS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
ACSS2 Antibody (Center) - Protein Information
Name ACSS2
Synonyms ACAS2
Function Activates acetate so that it can be used for lipid synthesis or for energy generation
Cellular Location Cytoplasm.

ACSS2 Antibody (Center) - Related products

AP13231c: ACSS2 Antibody (Center)

AP9606a: ACSS2 Antibody (N-term)

DC03336: Human ACSS2 cDNA Clone

LY14233a: ACSS2 Over-expression Lysate

BP9606a: ACSS2 Antibody (N-term) Blocking Peptide

ACSS2 Antibody (Center) - Application data

ACSS2 Antibody (Center) (Cat. #AP13231c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ACSS2 antibody detected the ACSS2 protein (arrow).
ACSS2 Antibody (Center) (Cat. #AP13231c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACSS2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

ACSS2 Antibody (Center) - Research Areas

Antibodies Biological Process Metabolic Process Primary Metabolic Process Lipid Metabolic Process Lipid Biosynthetic Process Biosynthetic Process Cellular Compartment Cytoplasm Nucleolus Nucleus Intracellular Part Intracellular Cytoplasmic Part Membrane-bounded Organelle Intracellular Membrane-bounded Organelle Membrane-enclosed Lumen Organelle Lumen Cytosol Organelle Intracellular Organelle Intracellular Organelle Lumen Organelle Part Intracellular Organelle Part Nuclear Lumen Nuclear Part Disease Melanoma Molecular Function Catalytic Activity Protein Binding Purine Nucleotide Binding Nucleotide Binding Ribonucleotide Binding Purine Ribonucleotide Binding Purine Nucleoside Binding Nucleoside Binding Adenyl Nucleotide Binding ATP Binding Adenyl Ribonucleotide Binding Ligase Activity Pathway KEGG Melanoma Glycolysis / Gluconeogenesis Tissue Blood Muscle Skin Platelet Melanoma

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BACKGROUND

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

REFERENCES

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Yilmaz, S., et al. Genomics 96(1):57-65(2010) Ban, H.J., et al. BMC Genet. 11, 26 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Yun, M., et al. J. Nucl. Med. 50(8):1222-1228(2009)