|Application ||WB, E|
|Calculated MW||74890 Da|
|Antigen Region||205-233 aa|
|Other Names||GTPase IMAP family member 8, Immune-associated nucleotide-binding protein 9, IAN-9, Protein IanT, GIMAP8, IAN9, IANT|
|Target/Specificity||This GIMAP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the N-terminal region of human GIMAP8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GIMAP8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections.|
|Cellular Location||Endoplasmic reticulum. Golgi apparatus. Mitochondrion. Cytoplasm, cytosol|
|Tissue Location||Expressed in the spleen, intestine, liver, and colon, as well as in lung, placenta, kidney, muscle, and heart Extremely low expression, if any, in brain, in thymus, bone marrow, and blood leukocytes (PubMed:15474311). Detected in T- cells (PubMed:23454188).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Dion, C., et al. Int. Immunol. 17(9):1257-1268(2005)
Krucken, J., et al. Gene 341, 291-304 (2004) :
Cambot, M., et al. Blood 99(9):3293-3301(2002)
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