|Application ||WB, IHC-P, FC, E|
|Calculated MW||55493 Da|
|Antigen Region||301-329 aa|
|Other Names||Monocarboxylate transporter 10, MCT 10, Aromatic amino acid transporter 1, Solute carrier family 16 member 10, T-type amino acid transporter 1, SLC16A10, MCT10, TAT1|
|Target/Specificity||This SLC16A10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-329 amino acids from the C-terminal region of human SLC16A10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC16A10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sodium-independent transporter that mediates the uptake of aromatic acids. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Basolateral cell membrane|
|Tissue Location||Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.
Loubiere, L.S., et al. Placenta 31(4):295-304(2010)
Friesema, E.C., et al. Mol. Endocrinol. 22(6):1357-1369(2008)
Broer, S. Physiol. Rev. 88(1):249-286(2008)
Park, S.Y., et al. Arch. Pharm. Res. 28(4):421-432(2005)
Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)
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